منابع مشابه
Insidious cognitive decline in CADASIL.
BACKGROUND AND PURPOSE Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) causes repeated ischemic attacks leading to subcortical vascular dementia. The aim of this study was to characterize cognitive function in subjects with a C475T (R133C) mutation in the Notch3 gene, leading to CADASIL. METHODS Prestroke (n=13) and poststroke (n=13) mutati...
متن کاملMRI correlates of cognitive decline in CADASIL: a 7-year follow-up study.
BACKGROUND Cognitive decline is one of the clinical hallmarks of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a cerebrovascular disease caused by NOTCH3 mutations. In this 7-year follow-up study, we aimed to determine whether there are associations between the different radiologic hallmarks in CADASIL and decline in specific cognitive dom...
متن کاملArticulatory agility in cognitive decline.
OBJECTIVE Motor speech disorders are believed to be uncommon in early Alzheimer's disease (AD). However, data from maximum performance tests of motor speech function in AD and related disorders are virtually nonexistent. The aim of this study was to make such data available. MATERIALS AND METHODS Sequential speech motion rate was analyzed in 236 memory clinic patients with different levels of...
متن کاملSubjective Cognitive Decline
Andrea Talesa,∗, Frank Jessenb,c, Christopher Butlerd, Gordon Wilcockd, Judith Phillipse and Tony Bayerf aCollege of Human and Health Sciences, Department of Psychology, Swansea University, Swansea, Wales, UK bDepartment of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany cGerman Center for Neurodegenerative Disorders (DZNE), Germany dNuffield Department of Clinical Neurosci...
متن کاملAge-associated cognitive decline.
INTRODUCTION Age-associated cognitive decline-or normal (non-pathological, normative, usual) cognitive ageing-is an important human experience which differs in extent between individuals. The determinants of the differences in age-related cognitive decline are not fully understood. Progress in the field is taking place across many areas of biomedical and psychosocial sciences. AREAS OF AGREEM...
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ژورنال
عنوان ژورنال: Stroke
سال: 2004
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000129787.92085.0a